MGF dosage chart
5 mg Vial
MGF is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols. A 5 mg vial reconstituted with bacteriostatic water yields about 1.67 mg/mL. This information is for research and educational use only.
- Reconstitute
- Add 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration.
- Typical daily range
- 100–300 mcg once daily (gradual titration).
- Easy measuring
- At 1.67 mg/mL, 1 unit = 0.01 mL ≈ 16.7 mcg on a U‑100 insulin syringe.
- Storage
- Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); use within ~30 days.
Dosing schedule
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Week 1 | 100 mcg (0.1 mg) | 6 units (0.06 mL) |
| Week 2 | 150 mcg (0.15 mg) | 9 units (0.09 mL) |
| Week 3 | 200 mcg (0.2 mg) | 12 units (0.12 mL) |
| Week 4 | 250 mcg (0.25 mg) | 15 units (0.15 mL) |
| Weeks 5–8 | 300 mcg (0.3 mg) | 18 units (0.18 mL) |
Reconstitution steps
- 1Draw 3.0 mL bacteriostatic water with a sterile syringe.
- 2Inject slowly down the vial wall; avoid foaming.
- 3Gently swirl/roll until dissolved (do not shake).
- 4Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light; use within approximately 30 days.
Important Notes
Practical considerations for consistency and safety.
- Use new sterile insulin syringes; dispose in a sharps container.
- Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation.
- Inject slowly; wait a few seconds before withdrawing the needle.
- Document daily dose and site rotation to maintain consistency.
- MGF has a short half‑life; PEGylated forms (PEG‑MGF) offer extended duration but follow different protocols.
How This Works
MGF is generated through alternative splicing of the IGF‑1 gene in response to mechanical loading or tissue injury. The resulting peptide contains a unique C‑terminal E domain that distinguishes it from systemic IGF‑1. Preclinical research demonstrates MGF activates satellite cells (muscle stem cells), promotes osteoblast proliferation, and supports neurogenesis. These effects appear to be localized and transient, suggesting MGF acts primarily as a tissue‑specific repair signal rather than a systemic growth factor.
Potential Benefits & Side Effects
Observations from preclinical literature (no formal human clinical trials have been completed).
- Promotes satellite cell activation and myoblast proliferation in muscle tissue.
- Supports bone defect healing and osteoblast activity in animal models.
- May promote neurogenesis and neuroprotection in aging brain tissue.
- Generally well tolerated in preclinical settings; occasional mild injection‑site reactions may occur with subcutaneous administration.
- Long‑term safety data in humans is limited; preclinical models suggest localized rather than systemic effects.
Lifestyle Factors
Complementary strategies for best outcomes.
- Pair with resistance training to provide the mechanical stimulus that naturally upregulates MGF expression.
- Ensure adequate protein intake (1.6–2.2 g/kg) to support tissue repair processes.
- Prioritize sleep and recovery; growth factor activity is enhanced during rest periods.
- Manage inflammation through balanced nutrition to optimize the repair environment.
Injection Technique
General subcutaneous guidance from clinical best‑practice resources.
- Clean the vial stopper and skin with alcohol; allow to dry.
- Pinch a skinfold; insert the needle at 45–90° into subcutaneous tissue.
- Do not aspirate for subcutaneous injections; inject slowly and steadily.
- Rotate sites systematically (abdomen, thighs, upper arms) by at least 1–1.5 inches from prior sites to avoid irritation.
- Use 23–25 gauge, 5/8‑inch needles for subcutaneous administration.
important-note
This content is for educational purposes only and is not medical advice.
MGF dosage FAQs
How much bacteriostatic water do you use to reconstitute MGF?
Add 3.0 mL bacteriostatic water → ~1.67 mg/mL concentration. for a 5 mg Vial vial. Add the water slowly against the inside wall of the vial and swirl — never shake — until the powder fully dissolves.
What does the MGF dosing schedule look like?
Week 1 — 100 mcg (0.1 mg) — 6 units (0.06 mL); Week 2 — 150 mcg (0.15 mg) — 9 units (0.09 mL); Week 3 — 200 mcg (0.2 mg) — 12 units (0.12 mL); Week 4 — 250 mcg (0.25 mg) — 15 units (0.15 mL). The full table above lists every step with matching syringe units.
What are the mixing steps for MGF?
Draw 3.0 mL bacteriostatic water with a sterile syringe. Inject slowly down the vial wall; avoid foaming. Gently swirl/roll until dissolved (do not shake).
How should reconstituted MGF be stored?
Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); use within ~30 days..
How many insulin syringe units equal a MGF dose?
Units depend on the water volume you used. Divide your target dose by the vial concentration to get millilitres, then multiply by 100 — 1 unit on a U-100 insulin syringe is 0.01 mL. The Spartan Peptides reconstitution calculator does this conversion for you.
Is MGF approved for human use?
No. MGF is sold and referenced strictly as a research chemical. Nothing on this page is medical advice and the material is not for human consumption.
Educational and research information only. Not medical advice, not for human consumption. Values are reference figures — always verify your own math with the reconstitution calculator.
On any insulin syringe, 1 unit = 0.01 mL, so unit counts above hold across brands.