GHRP-2 dosage chart
10 mg Vial
GHRP-2 is dosed at 100 mcg–300 mcg daily via subcutaneous injection in educational protocols. A 10 mg vial reconstituted with bacteriostatic water yields about 3.33 mg/mL. This information is for research and educational use only.
- Reconstitute
- Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration.
- Typical daily range
- 100–300 mcg once daily (gradual titration).
- Easy measuring
- At 3.33 mg/mL, 1 unit ≈ 33.3 mcg on a U‑100 insulin syringe.
- Storage
- Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
- Injection frequency
- Once daily — 5 days on, 2 days off (dose Mon–Fri, rest Sat–Sun).
- Dosing schedule
- 5 days on / 2 days off: dose Monday through Friday, then take Saturday and Sunday off. That is 5 dosing days per week.
Dosing schedule
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 100 mcg (0.1 mg) | 3 units (0.03 mL) |
| Weeks 3–4 | 150 mcg (0.15 mg) | 4.5 units (0.045 mL) |
| Weeks 5–8 | 200 mcg (0.2 mg) | 6 units (0.06 mL) |
| Weeks 9–12 (optional) | 250–300 mcg (0.25–0.3 mg) | 7.5–9 units (0.075–0.09 mL) |
Reconstitution Steps
| Phase | Per‑Injection Dose (mcg) | Frequency | Units (per injection) (mL) |
|---|---|---|---|
| Phase 1 (Weeks 1–2) | 100 mcg (0.1 mg) | 2× daily | 3 units (0.03 mL) |
| Phase 2 (Weeks 3–4) | 150 mcg (0.15 mg) | 2× daily | 4.5 units (0.045 mL) |
| Phase 3 (Weeks 5–8) | 200 mcg (0.2 mg) | 2–3× daily | 6 units (0.06 mL) |
Reconstitution steps
- 1Draw 3.0 mL bacteriostatic water with a sterile syringe.
- 2Inject slowly down the vial wall; avoid foaming.
- 3Gently swirl/roll until dissolved (do not shake).
- 4Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Dosing Cycle & Timing
This protocol runs on a 5 days on / 2 days off cycle.
- Cycle: 5 days on, 2 days off — dose Monday through Friday and rest on the weekend.
- 5 dosing days per week; the 2 off days help limit receptor desensitisation and give injection sites time to recover.
- Keep the dose time consistent on dosing days.
- If a weekday dose is missed, take it the same day if possible — do not dose on an off day to catch up.
- Weekly totals in the supplies and shopping lists are calculated on 5 dosing days, not 7.
Important Notes
Practical considerations for consistency and safety.
- Use new sterile insulin syringes for each injection; dispose in a sharps container.
- Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation.
- Inject slowly; wait a few seconds before withdrawing the needle.
- A 5‑days‑on/2‑days‑off schedule may help maintain GH response sensitivity over long protocols.
- Document daily dose and site rotation to maintain consistency.
How This Works
GHRP-2 is a growth hormone‑releasing peptide that acts as a ghrelin receptor agonist (GHS‑R1a). By binding to receptors in both the pituitary and hypothalamus, it triggers robust, pulsatile GH release that mimics natural secretion patterns. Clinical studies have demonstrated that even a single 100 mcg subcutaneous dose can raise GH levels several‑fold above baseline. When administered consistently, GHRP-2 can elevate IGF‑1 levels over weeks to months. However, the GH response may attenuate with continuous daily use (tachyphylaxis), which is why titration strategies and periodic breaks are often incorporated.
Potential Benefits & Side Effects
Observations from preclinical and clinical literature.
- Potent stimulation of endogenous GH release without suppressing natural production.
- Elevation of IGF‑1 levels with sustained administration (~50% increase reported in some studies).
- Used clinically as a diagnostic tool for GH deficiency evaluation.
- May support recovery, body composition, and sleep quality (anecdotally reported).
- Increased appetite (ghrelin‑mimetic action) — especially pronounced shortly after injection.
- Transient flushing, warmth, or tingling at injection site.
- Possible mild increases in cortisol and prolactin at higher doses.
- Water retention or joint stiffness with prolonged high‑dose use.
- Response attenuation (tachyphylaxis) with continuous daily dosing.
Lifestyle Factors
Complementary strategies for best outcomes.
- Administer on an empty stomach or before sleep to optimize GH pulse amplitude.
- Pair with a balanced, protein‑forward diet tailored to energy needs and recovery goals.
- Combine resistance training and aerobic activity to support GH/IGF‑1 axis benefits.
- Prioritize 7–9 hours of quality sleep to synergize with natural nocturnal GH secretion.
- Manage stress levels, as elevated cortisol can blunt GH response.
Injection Technique
General subcutaneous guidance from clinical best‑practice resources.
- Clean the vial stopper and skin with alcohol; allow to dry.
- Pinch a skinfold; insert the needle at 45–90° into subcutaneous tissue.
- For very lean individuals, use a 45° angle to avoid intramuscular injection.
- Inject slowly and steadily; do not aspirate for subcutaneous injections.
- Rotate sites systematically (abdomen at least 2 inches from navel, thighs, upper arms) to avoid lipohypertrophy.
- Dispose of used syringes immediately in a sharps container; never recap needles.
Important Note
This content is intended for therapeutic educational purposes only and does not constitute medical advice, diagnosis, or treatment.
Supplies needed
Plan covers the full 12-week protocol at the lowest listed starting dose: 0.1 mg per dose, 5 days on / 2 days off (60 administrations in total), using 10 mg vials. After mixing with 3 mL, the concentration is 3.33 mg/mL and each dose requires 0.03 mL total.
GHRP-2 vials (10 mg each)
Vials are rounded up only after calculating the whole protocol: ceil(6 ÷ 10) = 1. Usable peptide remaining in an opened vial carries forward to the next dose.
- Full protocol (12 weeks)
- 1 vial (6 mg needed ÷ 10 mg)
Insulin syringes (U-100, 1 mL)
One fresh syringe per administration.
- Full protocol (12 weeks)
- 60 syringes
Bacteriostatic water (10 mL bottles)
Use 3 mL per vial for reconstitution (1 × 3 mL = 3 mL).
- Full protocol (12 weeks)
- 1 × 10 mL bottle
Alcohol swabs
One for the vial stopper per draw + one for each injection site (5 days on / 2 days off). Recommend 2 × 100-count boxes.
- Full protocol (12 weeks)
- 120 swabs
| Supply | Full protocol (12 weeks) |
|---|---|
| GHRP-2 vials (10 mg each)Vials are rounded up only after calculating the whole protocol: ceil(6 ÷ 10) = 1. Usable peptide remaining in an opened vial carries forward to the next dose. | 1 vial (6 mg needed ÷ 10 mg) |
| Insulin syringes (U-100, 1 mL)One fresh syringe per administration. | 60 syringes |
| Bacteriostatic water (10 mL bottles)Use 3 mL per vial for reconstitution (1 × 3 mL = 3 mL). | 1 × 10 mL bottle |
| Alcohol swabsOne for the vial stopper per draw + one for each injection site (5 days on / 2 days off). Recommend 2 × 100-count boxes. | 120 swabs |
GHRP-2 dosage FAQs
How much bacteriostatic water do you use to reconstitute GHRP-2?
Add 3.0 mL bacteriostatic water → ~3.33 mg/mL concentration. for a 10 mg Vial vial. Add the water slowly against the inside wall of the vial and swirl — never shake — until the powder fully dissolves.
How often is GHRP-2 administered in research protocols?
Injection frequency: Once daily — 5 days on, 2 days off (dose Mon–Fri, rest Sat–Sun).
What does the GHRP-2 dosing schedule look like?
Weeks 1–2 — 100 mcg (0.1 mg) — 3 units (0.03 mL); Weeks 3–4 — 150 mcg (0.15 mg) — 4.5 units (0.045 mL); Weeks 5–8 — 200 mcg (0.2 mg) — 6 units (0.06 mL); Weeks 9–12 (optional) — 250–300 mcg (0.25–0.3 mg) — 7.5–9 units (0.075–0.09 mL). The full table above lists every step with matching syringe units.
What are the mixing steps for GHRP-2?
Draw 3.0 mL bacteriostatic water with a sterile syringe. Inject slowly down the vial wall; avoid foaming. Gently swirl/roll until dissolved (do not shake).
How should reconstituted GHRP-2 be stored?
Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles..
How many insulin syringe units equal a GHRP-2 dose?
Units depend on the water volume you used. Divide your target dose by the vial concentration to get millilitres, then multiply by 100 — 1 unit on a U-100 insulin syringe is 0.01 mL. The Spartan Peptides reconstitution calculator does this conversion for you.
Is GHRP-2 approved for human use?
No. GHRP-2 is sold and referenced strictly as a research chemical. Nothing on this page is medical advice and the material is not for human consumption.
Educational and research information only. Not medical advice, not for human consumption. Values are reference figures — always verify your own math with the reconstitution calculator.
On any insulin syringe, 1 unit = 0.01 mL, so unit counts above hold across brands.